药品信息:
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201961016513438.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- 部分中文托拉塞米处方资料(仅供参考)
【英文名称】Torem
【适用证】
原发性高血压; 充血性心力衰竭引起的水肿; 肝,肺或肾水肿。
【用法用量】
成年人
原发性高血压:建议每日一次服用2.5mg托拉塞米。 如有必要,可将剂量每日一次增加至5mg。 研究表明,每日5mg以上的剂量不会导致血压进一步降低。 在连续治疗约12周后表现出最大效果。
水肿:通常的剂量是每天一次5mg。 如有必要,剂量可逐步增加至20mg,每日一次。 在个别情况下,每天施用40mg托拉塞米。
【特殊警告和使用注意事项】
治疗前必须纠正低钾血症,低钠血症,低血容量和排尿障碍。
对于使用托拉塞米的长期治疗,建议定期监测血液中的电解质平衡,葡萄糖,尿酸,肌酸酐和脂质。
建议仔细监测有高尿酸血症和痛风倾向的患者。 应监测潜伏或明显糖尿病患者的碳水化合物代谢。
对于产生血压变化的其他药物,服用托拉塞米的患者如果出现头晕或相关症状,应警告不要开车或操作机器。
葡萄糖不耐受罕见遗传问题的患者,葡萄糖 - 半乳糖吸收不良的Lapp乳糖酶不应服用此药。
【禁忌】
无尿的肾功能衰竭; 肝昏迷和前昏迷;低血压; 预先存在的低血容量; 怀孕和哺乳期; 对托拉塞米和磺脲类药物过敏; 心律失常,与氨基糖苷类或头孢菌素同时治疗,或由于引起肾脏损害的药物引起的肾功能障碍。
【 Therapeutic indications】
Essential hypertension; oedema due to congestive heart failure; hepatic, pulmonary or renal oedema.
【Posology and method of administration】
Adults
Essential hypertension: A dose of 2.5mg torasemide once daily is recommended. If necessary, the dose may be increased to 5mg once daily. Studies suggest that doses above 5mg daily will not lead to further reduction in blood pressure. The maximum effect is exhibited after approximately twelve weeks of continuous treatment.
Oedema: The usual dose is 5mg once daily. If necessary, the dose can be increased stepwise up to 20mg once daily. In individual cases, as much as 40mg torasemide/day has been administered.
【Contraindications】
Renal failure with anuria; hepatic coma and pre-coma; hypotension; pre-existing hypovolaemia; pregnancy and lactation; hypersensitivity to torasemide and sulphonylureas; cardiac arrhythmias, simultaneous therapy with aminoglycosides or cephalosporins, or renal dysfunction due to drugs which cause renal damage.
【Special warnings and precautions for use】
Hypokalaemia, hyponatraemia, hypovolaemia and disorders of micturition must be corrected before treatment.
On long-term treatment with torasemide, regular monitoring of the electrolyte balance, glucose, uric acid, creatinine and lipids in the blood, is recommended.
Careful monitoring of patients with a tendency to hyperuricaemia and gout is recommended. Carbohydrate metabolism in latent or manifest diabetes mellitus should be monitored.
As for other drugs which produce changes in blood pressure, patients taking torasemide should be warned not to drive or operate machinery if they experience dizziness or related symptoms.
Patients with rare hereditary problems of glucose intolerance, the Lapp lactase deficiency of glucose-galactose malabsorption should not take this medication.
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201961016513438.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- |