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  药店国别: 英国药房
产地国家: 英国
所属类别: 作用于呼吸系统药物->肺炎
处方药:处方药
包装规格: 500毫克 21粒/盒
计价单位:
  点击放大  
生产厂家英文名:
FLYNN PHARMACEUTICALS
该药品相关信息网址1:
https://www.flynnpharma.com/products/healthcare-professionals/licensed-products/distaclor
原产地英文商品名:
Distaclor 500mg 21caps/box (Minimum order: 20)
原产地英文药品名:
cefaclor monohydrate
中文参考商品译名:
Distaclor 500毫克 21粒/盒 (最低起购量:20)
中文参考药品译名:
头孢克洛一水合物
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
pneumonia
英文适应病症2:
bronchitis
英文适应病症3:
Otitis media
英文适应病症4:
kin and soft tissue infections
英文适应病症5:
Urinary tract infections
临床试验期:
完成
中文适应病症参考翻译1:
肺炎
中文适应病症参考翻译2:
支气管炎
中文适应病症参考翻译3:
中耳炎
中文适应病症参考翻译4:
皮肤和软组织感染
中文适应病症参考翻译5:
尿路感染
药品信息:

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 详细处方信息以本药内容附件PDF文件(20194219492332.pdf)的“原文Priscribing Information”为准
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 部分中文Distaclor处方资料(仅供参考)


【英文名称】
Distaclor

【适用证】

Distaclor适用于治疗因易感微生物引起的下列感染:

呼吸道感染,包括肺炎,支气管炎,慢性支气管炎急性加重,咽炎和扁桃体炎,以及鼻窦炎治疗的一部分

中耳炎

皮肤和软组织感染

尿路感染,包括肾盂肾炎和膀胱炎

已发现Distaclor在急性和慢性尿路感染中均有效。 头孢克洛通常可有效地从鼻咽部根除链球菌,然而,无法获得在随后预防风湿热或细菌性心内膜炎中确立疗效的数据。

【用法用量】

剂量学

成人:通常的成人剂量为每8小时250mg。对于更严重的感染或由易感性较低的生物引起的感染,剂量可能增加一倍。每天4g的剂量已安全地给予正常受试者28天,但总日剂量不应超过该量。

Distaclor可在肾功能受损的情况下给药。在这种情况下,剂量通常不变(参见“特殊警告和使用特殊注意事项”)。

接受血液透析的患者:血液透析使血清半衰期缩短25-30%。在接受常规血液透析的患者中,建议在透析前给予250mg-1g的负荷剂量,并在透析期间每6至8小时给予250-500mg的治疗剂量。

老人:至于成年人。

儿科人群

如图所示,儿童通常推荐的每日剂量为20mg / kg /天,每8小时分剂量。对于支气管炎和肺炎,剂量为20mg / kg /天,分次剂量,每日3次。对于中耳炎和咽炎,可以每12小时分开并施用总日剂量。尚未确定用于少于一个月的婴儿的安全性和有效性。

【警告】

对活性物质或6.1节中列出的任何赋形剂过敏。

对其他头孢菌素过敏。

【Therapeutic indications】

Distaclor is indicated for the treatment of the following infections due to susceptible micro-organisms:

espiratory tract infections, including pneumonia, bronchitis, exacerbations of chronic bronchitis, pharyngitis and tonsillitis, and as part of the management of sinusitis

Otitis media

Skin and soft tissue infections

Urinary tract infections, including pyelonephritis and cystitis

Distaclor has been found to be effective in both acute and chronic urinary tract infections.

Cefaclor is generally effective in the eradication of streptococci from the nasopharynx, however, data establishing efficacy in the subsequent prevention of either rheumatic fever or bacterial endocarditis are not available.
 

【Posology and method of administration】

Posology

Adults: The usual adult dosage is 250mg every eight hours. For more severe infections or those caused by less susceptible organisms, doses may be doubled. Doses of 4g per day have been administered safely to normal subjects for 28 days, but the total daily dosage should not exceed this amount.

Distaclor may be administered in the presence of impaired renal function. Under such conditions dosage is usually unchanged (see 'Special Warning and Special Precautions for Use').

Patients undergoing haemodialysis: Haemodialysis shortens serum half-life by 25-30%. In patients undergoing regular haemodialysis, a loading dose of 250mg-1g administered prior to dialysis and a therapeutic dose of 250-500mg every six to eight hours maintained during interdialytic periods is recommended.

The elderly: As for adults.

Paediatric population

The usual recommended daily dosage for children is 20mg/kg/day in divided doses every eight hours, as indicated. For bronchitis and pneumonia, the dosage is 20mg/kg/day in divided doses administered 3 times daily. For otitis media and pharyngitis, the total daily dosage may be divided and administered every 12 hours. Safety and efficacy have not been established for use in infants aged less than one month.
 

【Contraindications】

Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.

Hypersensitivity to other cephalosporins.
 

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 详细处方信息以本药内容附件PDF文件(20194219492332.pdf)的“原文Priscribing Information”为准
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更新日期: 2019-4-1
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