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详细处方信息以本药内容附件PDF文件（201931820333430.pdf）的“原文Priscribing Information”为准
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部分中文顺铂注射液处方资料（仅供参考）

【英文名称】CISplatin

【适用证】

顺铂注射剂表示如下使用的治疗：

转移性睾丸肿瘤：

在已经接受适当手术和/或放射治疗程序的转移性睾丸肿瘤患者中与其他批准的化学治疗剂建立的联合治疗。

晚期膀胱癌： 顺铂注射液被指示为患有过渡性膀胱癌的患者的单一药剂，其不再适合局部治疗，例如手术和/或放射疗法。

【用法用量】

顺铂注射液通过缓慢静脉输注给药。快速静脉注射不应给予顺铂注射。

注意：含有可能与顺铂注射液接触的铝部件的针头或静脉注射液不应用于制备或给药。铝与注射液反应，导致沉淀物形成和效力丧失。

转移性睾丸肿瘤：

用于治疗睾丸癌的常用顺铂注射剂量与其他批准的化学治疗剂组合，每天20mg / m IV，每个周期5天。

转移性卵巢肿瘤：

与环磷酰胺联合治疗转移性卵巢肿瘤的常用顺铂注射剂量为每周期每周期75至100 mg / m IV（第1天）。

当与顺铂注射液组合使用时，环磷酰胺的剂量为每4周一次600mg / m IV（第1天）。

关于环磷酰胺给药的说明，请参阅环磷酰胺包装说明书。

在联合治疗中，顺序给予顺铂注射液和环磷酰胺。

作为单一药物，顺铂注射液应以每周期100mg / m IV的剂量给药，每四周一次。

晚期膀胱癌 顺铂注射剂应作为单一药剂以每周期50至70mg / m IV的剂量每3至4周施用一次，这取决于先前暴露于放射疗法和/或先前化学疗法的程度。对于预处理严重的患者，建议每4周重复一次50 mg / m的初始剂量。

【INDICATIONS】

Cisplatin Injection is indicated as therapy to be employed as follows:

Metastatic Testicular Tumors:

In established combination therapy with other approved chemotherapeutic agents in patients with metastatic testicular tumors who have already received appropriate surgical and/or radiotherapeutic procedures.

Advanced Bladder Cancer:

Cisplatin Injection is indicated as a single agent for patients with transitional cell bladder cancer which is no longer amenable to local treatments, such as surgery and/or radiotherapy.

【DOSAGE AND ADMINISTRATION】

Cisplatin Injection is administered by slow intravenous infusion. CISPLATIN INJECTION SHOULD NOT BE GIVEN BY RAPID INTRAVENOUS INJECTION.

Note: Needles or intravenous s ets containing aluminum parts that may come in contact with Cisplatin Injection should not be us ed for preparation or administration. Aluminum reacts with Injection, causing precipitate formation and a loss of potency.

Metastatic Testicular Tumors:

The usual Cisplatin Injection dose for the treatment of testicular cancer in combination with other approved chemotherapeutic agents is 20 mg/m IV daily for 5 days per cycle.

Metastatic Ovarian Tumors:

The usual Cisplatin Injection dose for the treatment of metastatic ovarian tumors in combination with cyclophosphamide is 75 to 100 mg/m IV per cycle once every four weeks (DAY 1).

The dose of cyclophosphamide when used in combination with Cisplatin Injection is 600 mg/m IV once every 4 weeks (DAY 1).

For directions for the administration of cyclophosphamide, refer to the cyclophosphamide package insert.

In combination therapy, Cisplatin Injection and cyclophosphamide are administered sequentially.

As a single agent, Cisplatin Injection should be administered at a dose of 100 mg/m IV per cycle once every four weeks.

Advanced Bladder Cancer

Cisplatin Injection should be administered as a single agent at a dose of 50 to 70 mg/m IV per cycle once every 3 to 4 weeks depending on the extent of prior exposure to radiation therapy and/or prior chemotherapy. For heavily pretreated patients an initial dose of 50 mg/m per cycle repeated every 4 weeks is recommended.

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详细处方信息以本药内容附件PDF文件（201931820333430.pdf）的“原文Priscribing Information”为准
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